Jo Jo Makoons Azure is a spirited seven-year-old who moves through the world a little differently than anyone else on her Ojibwe reservation. It always seems like her mom, her kokum (grandma), and her teacher have a lot to learn, about how good Jo Jo is at cleaning up, what makes a good rhyme, and what it means to be friendly. Even though Jo Jo loves her best friend Mimi (who is a cat), she's worried that she needs to figure out how to make more friends. Because Fern, her best friend at school, may not want to be friends anymore.