Eighty-six-year-old Mattie Snorgenson has had enough! She's spent most of her life caring for family and fitting into polite society. Now, she is ready to follow her dream. Inspired by Mattie's courage, four other senior women join her in escaping the boredom of life in their retirement home. Together they travel the world, each seeking to fulfill the one, secret desire she has always held. With help from a pierced, tattooed and dreadlocked granddaughter, the friends journey from Florida to the Emerald Isle, and from Tasmania to the markets of Egypt. When their story goes viral, surfers, hitchhikers, priests and a Crocodile Dundee impersonator pitch in to help the "outrageous grannies." Even Doctor Phil gets into the act. The ladies, must outsmart relatives, who seek to return them to "senior living," and conmen, who see them as easy targets. And, each must face her own frailties and mortality. Finally, forced to choose between the security of home and the danger of continuing their quest, ringleader Mattie is, challenged with the most important decision of her life.