Fast Facts: Thrombotic Thrombocytopenic Purpura
(eBook)
Thrombotic thrombocytopenic purpura (TTP) is a rare disorder of the blood coagulation system. In most cases, a lack of the ADAMTS13 enzyme leads to an accumulation of ultra-large von Willebrand factor molecules in the plasma, which, in turn, initiate the formation of microscopic thromboses in small blood vessels. TTP is a medical emergency. Timely diagnosis and urgent and effective management are vital, mortality in those untreated is in the region of 90%. The understanding of TTP pathogenesis has increased markedly in recent decades. It is now known that TTP is acquired (immunemediated) or congenital, and that the most common type, the acquired form, predominantly affects women in their 40s. It is also clear that the prompt delivery of plasma exchange saves lives. 'Fast Facts: Thrombotic Thrombocytopenic Purpura' sets out, in a clear and accessible format, the steps to suspecting, diagnosing and treating this potentially devastating disease. These steps are complemented by clear descriptions of the disease mechanism and epidemiology. Differential diagnosis, which is of the utmost importance for this disease, is explored in detail. Contents:- Disease overview- Clinical presentation- Differential diagnosis- Laboratory findings and diagnosis- Management
Notes
Scully, M. A. (2020). Fast Facts: Thrombotic Thrombocytopenic Purpura. [United States], S. Karger AG.
Chicago / Turabian - Author Date Citation (style guide)Scully, M. A.. 2020. Fast Facts: Thrombotic Thrombocytopenic Purpura. [United States], S. Karger AG.
Chicago / Turabian - Humanities Citation (style guide)Scully, M. A., Fast Facts: Thrombotic Thrombocytopenic Purpura. [United States], S. Karger AG, 2020.
MLA Citation (style guide)Scully, M. A.. Fast Facts: Thrombotic Thrombocytopenic Purpura. [United States], S. Karger AG, 2020.
Hoopla Extract Information
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title | Fast Facts: Thrombotic Thrombocytopenic Purpura |
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dateLastUpdated | Sep 29, 2021 06:13:20 PM |
Record Information
Last File Modification Time | Nov 23, 2023 01:01:23 AM |
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Last Grouped Work Modification Time | Nov 22, 2023 10:23:35 PM |
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